Successful Medical Rx of Candida albicans endocarditis in an
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Introduction
Fungal endocarditis (FE) may complicate 5% of invasive fungal infections (IFIs) in neonates; Candida albicans is the predominant fungus. Detection of an endocardiac mass and of positive blood culture suggest the diagnosis. Definite diagnosis requires surgical removal, pathological and microbiological examination of the mass. Reported mortality is up to 42.2%.

Case Report:
A female neonate, born at gestational age 27 weeks weighing 800 g, was admitted to our neonatal Intensive Care Unit (NICU). On admission, she was mechanically ventilated, treated with surfactant; umbilical venous catheter (UVC) was placed, and its tip was demonstrated by chest radiograph in the right atrium (RA). Minimal enteral feeding was started on day 1 with human donor bank milk and own mother milk. Fluconazole prophylaxis was not administered. On day 2 was estubated to nasal continuous positive airway pressure (CPAP). On day 7, full enteral feeding was achieved, parenteral nutrition stopped, and UVC removed. Initially leukopenic (lower leukocyte count was 3.43 × 109/L on day 1) and thrombocytopenic (lower platelet count was 22 × 109/L on day 5), the baby had normal leukocyte count on day 6, with platelet count rising to 57 × 109/L. Ampicillin and amikacin started on day 1 where administered for a total of 6 days.....

http://www.jcnonweb.com/article.asp?issn=2249-4847;year=2017;volume=6;issue=2;spage=94;epage=96;aulast=Cuna
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