Successful management of maternal factor VII deficiency in a
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Case report
The patient was 18 years old, gravida 1, para 0. Menstruation was irregular, and its duration was 5 to 7 days with a moderate amount of bleeding. She had no past surgical history but a number of dental extractions. She was referred to our hospital at 31+1 weeks of gestation due to known FVII deficiency. At 4 years old, she underwent a dental extraction and had prolonged, but not acute, unusual bleeding. She was referred to a pediatrician, and FVII deficiency was suspected based on hemostatic screening, which revealed an isolated prolongation of PT with a normal aPTT. A Factor assay to evaluate FVII activity (4%) confirmed the diagnosis. Factor II, V, and X were normal. Her family had no history of bleeding disorders. Genotyping for FVII was recommended, but her family declined due to financial concerns. After FVII deficiency was diagnosed, the patient had two times more dental extractions. She received FFP before each procedure to prevent excessive bleeding and she did not have any unusual bleeding. During the pregnancy, there was no vaginal spotting in the first trimester. Sonographic findings were normal and the fetal growth rate was appropriate for the gestational age.....

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124094/
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