Sudden temperature change can increase risk for allergic con
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A retrospective study showed a statistically significant relationship between allergic conjunctivitis risk and sudden change in temperature, which can be compounded with a decline in humidity. Patel and researchers evaluated the effect of temperature change on allergic conjunctivitis for patient. A case-crossover design was used, and all cases served as their own controls on a randomly selected day 90 to 250 days before their allergic conjunctivitis diagnosis. The researchers evaluated the daily risk for a hospital visit due to allergic conjunctivitis with exposure to temperature change for every day up to 30 days before their diagnosis. Researchers evaluated 74,951 patients who made 116,162 visits for allergic conjunctivitis. They found the adjusted standard deviation of temperature, the hourly temperature change, increased the risk for allergic conjunctivitis for all 30 days before diagnosis. The highest odds were 1 day before diagnosis (P .001).

Results suggest a positive relationship between exposure to temperature change and risk for allergic conjunctivitis. As high as 2.7% increased odds for allergic conjunctivitis hospital visit was observed. Additionally, a decline in relative humidity and the absolute temperature-humidity interaction increased risk for all 30 days. Temperature alone increased risk between 30 days and 4 days before diagnosis. Finally, researchers stratified findings geographically and found the Lower Midwest and Northeast demonstrated the strongest relationship between temperature change and allergic conjunctivitis risk.