Suppressing a DNA-repairing protein in brain could be key to
Targeting a specific DNA-repairing protein in the brain could be an effective way to treat the most aggressive type of brain tumour, a study suggests.

Researchers at the University of Leeds found that inhibiting this protein, called RAD51, helped increase the effectiveness of radiotherapy in killing off glioblastoma cells in the lab.

Glioblastoma is the most common type of primary brain tumour in adults and also the most aggressive. Many patients will not survive their disease despite intensive treatment.

It' s thought a subgroup of glioblastoma cells are able to reproduce to make identical copies of themselves and are more resistant to treatment.

In the new study, the researchers found that this subgroup of cells, called Glioblastoma Stem Cells, have a large amount of the RAD51 inside them....