The Mystery of Deadly Outbreaks in India, that baffled docto
Dr. Binal Doshi
The Mystery of Deadly Outbreaks in India, that baffled doctors for 20 years
For 20 years, in mid-May, in Muzaffarpur, as temperatures reached scorching heights, parents took children who had been healthy the night before to the hospital. The children awakened with a high-pitch cry in the early morning, many parents said. Then the youths began having seizures and slipping into comas. In about 40 percent of cases, they died. Every year in July, with the arrival of monsoon rains, the outbreak ended as suddenly as it began.

Clue 1 - There was no evidence the children had infections. Temperature, WBC - normal. All children had encephalopathy

Clue 2 - Most of the victims had very low blood sugar levels

Clue 3 - Affected children had huge metabolic imbalances - High levels of hypoglycin in urine

Can you solve this Medical Mystery?
S●●●●●p D●●●i and 16 others like this
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Dr. S●●●●●r  V●●●●●a
Dr. S●●●●●r V●●●●●a General Medicine
Malnutrition compromises the body' s ability to prevent hypoglycaemia .the toxin in unripe lichi is hypoglycin
Feb 5, 2017Like
Dr. B●●●l D●●●i
Dr. B●●●l D●●●i General Medicine
Hi, all very valid points - The deadly outbreaks were due to consumption of Lychee (Litchi) fruits on an empty stomach by malnourished children. The lychee fruit contains hypoglycin, a toxin that inhibits the body’s ability to synthesize glucose, leading to acute hypoglycemia, or low blood glucose levels. Investigations revealed huge amounts of hypoglycin in the urine of the affected children which validated the hypothesis. The investigators advised all parents to ensure that their children eat less lychees and that too always on after a meal instead of an empty stomach which ended the 20 year old medical mystery... Read more
Feb 6, 2017Like
Dr. F●●●●n K●●n
Dr. F●●●●n K●●n General Medicine
Thats great. :D....
Feb 6, 2017Like