The Physician who sacrificed himself for the cause of Medicine
Daniel Carrion was a Peruvian medical student. He established the link between acute and chronic forms of Oroya fever, a disease prevalent in Peru, Ecuador and Columbia.
Oroya fever or Carrion's disease is an infectious disease produced by Bartonella bacilliformis infection.
How did he establish this link?
By sacrificing himself.
He was inoculated by close friends with blood which had been taken from a wart of a 14-year-old patient. Carrión's aim was to prove a link between the acute blood stage of Oroya fever with that of the later chronic form of the disease, called verruga peruana, typified by numerous red, wart-like dermal nodules. Neither the cause nor mode of transmission of Oroya fever was then known and, furthermore, the relationship between the acute and chronic forms of the disease was not yet proven.
Carrión developed the classic symptoms of the acute phase of the disease, thereby establishing the link.
On October 7, 1991, the Peruvian government announced a law declaring Carrión to be a "National Hero" in his honour.