The “hook effect” causing a negative pregnancy test in a pat
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Complete molar pregnancy is estimated to occur once in every 1000–1500 pregnancies. It most commonly presents with vaginal bleeding between 6 and 16 weeks gestation in approximately 80–90% of cases. The other classic clinical signs and symptoms, such as uterine enlargement greater than expected for gestation dates, hyperemesis, and medical complications, such as pregnancy induced hypertension, clinical hyperthyroidism and respiratory insufficiency, occur less frequently in recent years. This has been a result of earlier diagnosis from increased availability of ultrasonography and accurate tests for measurement of human chorionic gonadotropin (hCG).We report a case of a complete mole and normal fetus twin gestation where the diagnosis was delayed by a negative pregnancy test due to the “hook effect,” resulting in life-threatening complications....

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5475266/
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Dr C●●●●●I S●●●●L
Dr C●●●●●I S●●●●L Obstetrics and Gynaecology
We too had a similar case recently..later dilution of a drop of urine with ns gave us a positive upt ????? hook effect or prozone effect
Aug 8, 2017Like1