The progress of regular cigarette smokers before 18 years is
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A Study was conducted to identify predictors of becoming a daily cigarette smoker over the course of 4 years. Researchers identified 12- to 24-year-olds at wave 1 of the US Population Assessment of Tobacco and Health Study and determined ever use, age at first use, and daily use through wave 4 for 12 tobacco products.

Results:
--62% of 12- to 24-year-olds tried tobacco, and 30.2% tried more than 5 tobacco products by wave 4.
--At wave 4, 12% were daily tobacco users, of whom 70% were daily cigarette smokers; daily cigarette smoking was 20.8% in 25- to 28-year-olds, whereas daily electronic cigarette (e-cigarette) vaping was 3.3%.
--Compared with single product triers, the risk of progressing to daily cigarette smoking was 15% points higher among those who tried more than 5 products.
--In particular, e-cigarette use increased the risk of later daily cigarette smoking by threefold (3% vs 10%; aRD 7%). Daily smoking was 6 percentage points lower (aRD ?6%) for those who experimented after age 18 years.

Studies concluded that trying e-cigarettes and multiple other tobacco products before age 18 years is strongly associated with later daily cigarette smoking. The recent large increase in e-cigarette use will likely reverse the decline in cigarette smoking among US young adults.

Source: https://pediatrics.aappublications.org/content/early/2021/01/08/peds.2020-025122?rss=1
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