The role of low-carb, low-sugar diets in warding off polycys
Ketogenic diets may be safe and effective in patients with polycystic kidney disease (PKD). The idea to use such diets originated from a mouse experiment conducted several years ago that researchers was not expecting to work at the time. But it did. Giving less food to lab mice whose genomes were manipulated to give them PKD led to a vast improvement in their kidney disease. Afterwards, the researchers team went on to identify the mechanism of the stunning effect and found that it was the metabolic state of ketosis. Many patients with PKD started to follow ketogenic diets attempting to slow down or even improve their disease that involves painful, fluid-filled cysts in the kidneys and affects millions of people worldwide, impairing the organs' function and often requiring dialysis in the later stages of the disease.

Source: https://academic.oup.com/ckj/article/15/6/1034/6571936?login=true
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