Those Discharged From Hospital After Covid Have Increased Ri
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People discharged from hospital after Covid-19 appear to have increased rates of organ damage compared with similar individuals in the general population, finds a study. The increase in risk was not confined to the elderly and was not uniform across ethnic groups, prompting the researchers to suggest that the long-term burden of Covid-19-related illness on hospitals and broader healthcare systems is likely to be substantial.

A team set out to compare rates of organ dysfunction in individuals with Covid-19 several months after discharge from hospital with a matched control group from the general population. Their findings are based on 47,780 individuals in a hospital in England with covid-19 who were discharged alive by 31 August 2020.

Participants were matched with controls, based on personal characteristics and medical history. Health records were then used to track rates of hospital readmission, death from any cause, and diagnoses of respiratory, cardiovascular, metabolic, kidney, and liver diseases until 30 September 2020.

Over an average follow-up of 140 days, nearly a third of individuals who were discharged from hospital after acute Covid-19 were readmitted and more than 1 in 10 died after discharge. These events occurred at rates of 766 readmissions and 320 deaths per 1,000 person-years, which were four and eight times greater, respectively, than those in matched controls.

Rates of respiratory disease, cardiovascular disease, and diabetes were also significantly raised in patients with Covid-19. Differences in rates of multiorgan dysfunction between patients with Covid-19 and matched controls were greater for individuals aged less than 70 than for those aged 70 or older, and in ethnic minority groups compared with the white population, with the largest differences seen for respiratory disease.