Timing smoking cessation attempts with women's hormone level
Fluctuations in ovarian hormones have been associated with changes in cigarette smoking behavior, which can be measured through both serum or less invasive salivary procedures. Nontreatment-seeking, cigarette-smoking women (n = 82; ages 18–45 years) provided daily salivary hormone samples every morning for 14 consecutive days. Time-dependent random effects functions were used to approximate daily salivary progesterone (ng/mL) levels over the course of a standardized menstrual cycle. Serum measures of progesterone from a previous study of female cigarette smokers were examined for consistency with established profiles and compared with the salivary profile using the same methodology. The pattern of salivary and serum progesterone measured across the menstrual cycle is similar in form, which is noteworthy given that the saliva and serum samples were drawn from independent samples of female smokers. Inter- and intra-individual variation in salivary measures may be greater than in serum measures.

Source: https://academic.oup.com/ntr/advance-article/doi/10.1093/ntr/ntac121/6582861?login=true