Too little or too much sleep may increase mortality risk
Sleeping less or more than 7 hours was significantly associated with an increased mortality risk in men and women, according to an East Asian study published in JAMA Network Open.

The association between long sleep duration and mortality appears stronger in East Asian populations than in North American or European populations.

This study aimed to assess the sex-specific association between sleep duration and all-cause and major-cause mortality in a pooled longitudinal cohort and to stratify the association by age and body mass index.

This cohort study of individual-level data from 9 cohorts in the Asia Cohort Consortium was performed from January 1, 1984, to December 31, 2002. The final population included participants from Japan, China, Singapore, and Korea. Mean (SD) follow-up time was 14.0 (5.0) years for men and 13.4 (5.3) years for women.

Mortality, including deaths from all causes, cardiovascular disease, cancer, and other causes were assessed. Sex-specific hazard ratios (HRs) and 95% CIs were estimated using Cox proportional hazards regression with shared frailty models adjusted for age and the key self-reported covariates of marital status, body mass index, smoking status, alcohol consumption, physical activity, history of diabetes and hypertension, and menopausal status (for women).

Results:
-- For 322721 participants (mean age, 54.5 years; 178542 female), 19419 deaths occurred among men (mean age of men, 53.6 years) and 13768 deaths among women (mean age of women, 55.3 years).

-- A sleep duration of 7 hours was the nadir for associations with all-cause, cardiovascular disease, and other-cause mortality in both men and women, whereas 8 hours was the mode sleep duration among men and the second most common sleep duration among women.

-- The association between sleep duration and all-cause mortality was J-shaped for both men and women.

-- The greatest association for all-cause mortality was with sleep durations of 10 hours or longer for both men and women.

-- Sex was a significant modifier of the association between sleep duration and mortality from cardiovascular disease, cancer, and other causes.

-- Age was a significant modifier of the associations among men only.

Conclusively, the findings of this cohort study suggest that sleep duration is a behavioral risk factor for mortality in both men and women. Age was a modifier of the association between sleep duration in men but not in women. Sleep duration recommendations in these populations may need to be considered in the context of sex and age.

Source: https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2783717
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