Tracking daily movement patterns may one day help predict de
Gradual disengagement from daily physical activity (PA) could signal present or emerging mild cognitive impairment (MCI) or Alzheimer’s disease (AD). Activity patterns, overall and by the time of day, were cross-sectionally compared between participants with adjudicated normal cognition (n=549) and MCI/AD diagnoses using covariate-adjusted regression models. Compared to those with normal cognition, those with MCI/AD had 2.1% higher activity fragmentation but similar mean total activity counts/day (p=0.075) and minutes/day spent active (p=0.174). Time-of-day analyses show MCI/AD participants had lower activity counts and minutes spent active during waking hours.