Transition of oral leukoplakia into oral verrucous carcinoma
Verrucous carcinoma (VC) is an exophytic lesion,which classically can be seen in the oral cavity, larynx, genitalia, skin, and esophagus. It has a slow growth potential and is an alternative form of oral squamous cell carcinoma. It is recognized by its local aggressiveness with minimal metastatic activity.

It is also called as “snuff dipper’s cancer” as its association with tobacco chewers and snuff users. According to a recent literature, VC has a strong relation with human papilloma virus which has a potential role in its growth and development. Though clinical presentation is classic for VC, histopathological diagnosis needs expertise opinion. It is said that often VC is preceeded by long standing potentially malignant disorders (PMD) in the oral cavity.

Published in the International Journal of Contemporary Medical Research, the authors report a case of verrucous carcinoma with a pre existing history of oral leukoplakia since long duration.The case was managed surgically and the patient is on follow up without any complication since a year.

Case highlights:-
• Potentially malignant disorders (PMD) of oral cavity should be correctly diagnosed and immediately the treatment should start to prevent further complications.

• Long term follow up of patients with PMD is must.

• The Prognosis of VC is often good after surgical treatment.

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