Treatment application of rivaroxaban in patients with lived
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Livedoid vasculopathy (LV) is a chronic prothrombotic disease of cutaneous microcirculation resulting in cutaneous ischemia and infarction. As a rare disease, LV has an estimated incidence of ten cases per million.1 LV mostly appears in late adolescence up to the age of 30 years, and patients with LV have an average age of 45 years. LV shows a distinct female preference and affects three times as many females as males. Not only correct diagnosis but also effective treatments are very difficult for patients with LV. Due to the lack of large-scale studies in this rare disease, LV poses a great challenge to the doctors,and existing treatment has always been an individual attempt with off-label application. The main goals in the treatment of patients with LV are to avoid the repeated occurrence of active cutaneous lesions and prevent painful ulceration and irreversible scarring......

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364015/
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