Treatment for Acute Stage Complex Regional Pain Syndrome Typ
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Complex regional pain syndrome (CRPS) type II is a syndrome that develops after nerve injury. Symptoms may be severe and vary depending on the degree of sympathetic nerve involvement. As yet, there is no satisfactory treatment. This article reports the case of a female patient who had an L5 left transverse process fracture and an S2 body fracture, who developed symptoms of CRPS type II in her left lower leg that were aggravated during ambulation in spite of absolute bed rest for one month after the trauma. Several treatments, including bed rest, medication and numerous nerve blocks were attempted, but the pain persisted. Injection of polydeoxyribonucleotide (PDRN) solution was given finally at the left L5 transverse process fracture site because of the anti-inflammatory effect of PDRN. One day after this treatment, her symptoms had almost disappeared and three days later, she was discharged.

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