Two aspirins a day helps keep bowel cancer away: Study
Aspirin can also reduce the risk of colorectal and endometrial (bowel or colon, rectal, stomach and womb) cancers in persons with Lynch syndrome.

The results of the 10-year-long study were published in the medical journal The Lancet on 12 June, led by Prof Sir John Burn and Prof D Timothy Bishop from the UK, had data analysis by Dr Harsh Sheth from Ahmedabad.

Key Findings:

• If a person with Lynch syndrome, takes two aspirins a day for an average of two and a half years, it reduces cancer risk by half.

• The randomized doubleblind trial covered 861 persons with Lynch Syndrome. They were given 600mg of aspirin or a placebo every day for two years, and were followed up with annually.

• “The data shows that among those who took aspirin for two years, there were 50% fewer bowel cancers,” said Dr Sheth, associated with the FRIGE’s Institute of Human Genetics.

• “Aspirin also reduced the risk of all Lynch syndrome cancers combined by about 37% in those patients.”

• How does the study affect the Indian population?

Prof Burn said India has comparatively lower risk factors such as consumption of red meat and obesity. “But with the changing socio-economic profile of the population, India could have higher incidence of cancer in the future,” he said.

Dr Sheth leads an ongoing study to detect prevalence of Lynch Syndrome in colorectal cancer patients in India. The study is funded by the Gujarat State Biotech Mission.

S S and 5 others like this1 share
S S General Medicine
The title is a bit misleading and should add the term ' in patients with Lynch Syndrome' in order to prevent the development of any misconception among the general public regarding the use of Aspirin. Though this article throws a positive light on the prophylactic use of Aspirin, the fact that it should be used selectively and cautiously, stands.
Jun 16, 2020Like2