UK warns people with serious allergies to avoid Pfizer COVID
Now open: Certificate Course in Management of Covid-19 by Govt. Of Gujarat and PlexusMDKnow more...Now open: Certificate Course in Management of Covid-19 by Govt. Of Gujarat and PlexusMDKnow more...
Get authentic, real-time news that helps you fight COVID-19 better.
Install PlexusMD App for doctors. It's free.
Britain's medicine regulator has advised that people with a history of significant allergic reactions do not get Pfizer-BioNTech's COVID-19 vaccine after two people reported adverse effects on the first day of rollout.

National Health Service medical director Stephen Powis said the advice had been changed after two NHS workers reported anaphylactoid reactions associated with receiving the vaccine.

The Medicines and Healthcare products Regulatory Agency (MHRA) was the first in the world to approve the vaccine, developed by Germany's BioNTech and Pfizer, last week, while the U.S. FDA and European Medicines Agency (EMA) continue to assess the data.

"Last evening, we were looking at two case reports of allergic reactions. We know from the very extensive clinical trials that this wasn't a feature," MHRA Chief Executive June Raine told lawmakers.

Pfizer has said people with a history of severe adverse allergic reactions were excluded from their late-stage trials.

The FDA released documents on 8 December in preparation for an advisory committee meeting, saying the Pfizer vaccine's efficacy and safety data met its expectations for authorization.

That briefing document said 0.63% of people in the vaccine group and 0.51% in the placebo group reported possible allergic reactions in trials, which Peter Openshaw, Professor of Experimental Medicine at Imperial College London, said was a very small number.

Dr. J●●●●●h A●●●●i and 10 others like this8 shares
Dr. A●●●●●h S●●●●a P●●●●l
Dr. A●●●●●h S●●●●a P●●●●l Physiotherapy
Dec 14, 2020Like