USPSTF: All pregnant women should be screened for syphilis e
A previous recommendation made by the U.S. Preventive Services Task Force, or USPSTF, suggesting that all pregnant women receive screening for syphilis early in pregnancy has been reaffirmed. This guidance was rated with a grade A.

These screenings should be conducted at the first prenatal visit and at approximately 28 weeks’ gestation.

The USPSTF noted that at any time during pregnancy, untreated syphilis in a woman can be transmitted to a fetus in utero or during birth and may result in stillbirth, neonatal death and other morbidities in neonates, including bone deformities and neurological impairments.

Both the CDC and a joint guideline issued by the AAP and the American College of Obstetricians and Gynecologists suggest that repeat screening is beneficial for pregnant women, especially those at high risk for infection, including those who live in areas with a high prevalence of syphilis, those with HIV and those who have been previously incarcerated or have a history of commercial sex work.

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