Ultrasonographic findings in bilateral diffuse Uveal melanoc
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A woman in her 60s presented with blurred vision and photophobia in both eyes, which had persisted for 3 months. She had previously been diagnosed with clear cell adenocarcinoma of the ovary in 2003 and was treated with surgical resection, with a total hysterosalpingo-oophorectomy, and chemotherapy administered as eight cycles of taxol and carboplatin. A gastric stromal tumor was then detected and surgically resected in 2012, and metastatic lymph nodes in the groin were detected in 2018. Her history of ocular surgery included cataract phacoemulsification and intraocular lens implantation for rapidly progressive cataracts in 2018.

On presentation, the patient’s best-corrected visual acuity (BCVA) was 20/32 in the right eye and 20/25 in the left eye. An ophthalmoscopic examination revealed a peripherally shallow anterior chamber, with iris pigmentation and an iris nodule in the anterior chamber in both eyes. The intraocular pressure was 25/26 mmHg in both eyes. A fundus examination showed multiple, irregularly shaped, elevated pigmented lesions in the peripheral retina, corresponding to multifocal early nummular areas of hyperfluorescence on FFA and reduced autofluorescence (AF). Optical coherence tomography (OCT) showed subretinal fluid in the right eye and irregular hyperreflective spots in both eyes. High-frequency B-scan ultrasonography revealed bilateral diffuse choroidal thickening and scattered choroidal nevi-like lesions. UBM showed a peripherally shallow anterior chamber, diffuse ciliary body thickening, ciliary body nevi-like lesions, and multiple ciliary body cysts.

Source:https://bmcophthalmol.biomedcentral.com/articles/10.1186/s12886-020-01720-6
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