Uncommon Complication, Visual loss after Gas Tamponade for
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A Study was conducted to identify the incidence rate and the clinical characteristics of unexplained visual loss after gas tamponade for primary macula-sparing rhegmatogenous retinal detachment.

A retrospective longitudinal study was performed on all subjects who had vitrectomy with gas for primary macula-on rhegmatogenous retinal detachment. After gas absorption, the outcome was unexplained visual loss, which was described as a loss of vision to less than 20/200 without obvious causes. The diagnostic process was examined.

Results:
--9 eyes with unexplained visual loss of 357 surgeries were found. The incidence proportion was 2.52 new cases every 1,000 eyes affected by macula-on rhegmatogenous retinal detachment treated with gas per year.

--All subjects had an absolute central scotoma, with a median postoperative visual acuity of 20/1,600 (counting fingers).

--Structural findings were consistent with an axonal damage; all eyes had microcystoid macular edema and reduced thickness of both macular ganglion cell and retinal nerve fiber layers.

--No photoreceptor structural damages were noted.

Finally, after gas tamponade for primary macula-on rhegmatogenous retinal detachment, the frequency of unexplained vision loss is 2.52 new cases each 1,000 eyes per year. This uncommon complication, which has been linked to axonal damage in retinal ganglion cells, is still a source of concern for vitreoretinal surgeons.

Source: https://journals.lww.com/retinajournal/Abstract/2021/05000/UNEXPLAINED_VISUAL_LOSS_AFTER_GAS_TAMPONADE_FOR.9.aspx
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