Upfront surgery does not improve OS for patients with HPV–ne
Upfront surgical resection did not improve OS compared with conventional concurrent chemoradiation therapy among patients with HPV–negative oropharyngeal squamous cell carcinoma, according to results of an observational study.
“The findings of this analysis do not negate the role of surgery in HPV–negative oropharyngeal squamous cell cancer [OPSCC]. Rather patients undergoing transoral robotic surgery who do not require concurrent chemoradiation [CRT] may have favorable quality of life in comparison with those receiving definitive CRT, a question currently under investigation,” Zain A. Husain, MD, assistant professor of therapeutic radiology, and director of the head and neck radiotherapy program at Smilow Cancer Hospital of Yale Cancer Center, and colleagues wrote.