Use of PVB Has No Effect on Cancer Survival
Contrary to some previous studies, the use of paravertebral block (PVB) is not associated with a reduced rate of cancer recurrence or improved survival after breast cancer surgery, new research suggests.

There are two major hypotheses on the possible connection between PVB and breast cancer recurrence, according to Juan P. Cata, MD, study author, and assistant professor of anesthesiology and perioperative medicine at the University of Texas MD Anderson Cancer Center, in Houston:

- PVB reduces a patient’s stress response during surgery, decreasing inflammation and catecholamines, which have been shown, biologically, to promote cancer growth.
- PVB reduces the use of intraoperative opioids, which have been found in some animal models to promote cancer growth....