Uveitis, A diagnostic factor in patients with spondyloarthri
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Spondylarthritis (SpA) is a group of diseases with overlapping skeletal and extra-articular features. Acute anterior uveitis (AAU) is the most common extra-articular manifestation of SpA.

A Study was conducted to analyze the frequency and factors associated with AAU in different forms of SpA in a large nationwide cohort of Turkish SpA patients.

The data was obtained from the TReasure database, in which there were compiled data from records of the web-based RA and SpA patients treated with biological disease modifying anti-rheumatismal drugs from different regions of Turkey. The clinical charecteristics of SpA and uveitis are recorded.

--Data of the 4297 SpA patients were included in the study. Overall, 475/4297 patients had experienced one or more episodes of uveitis.

--SpA patients with older age, a smoking history, delayed diagnosis, longer disease duration, arthritis, positive HLA-B27, a family history of SpA, and radiographic damage (presence of sacroiliitis, syndesmophytes, bamboo spine, hip involvement) more commonly had uveitis.

--On the other hand, uveitis was less prevalent in patients with psoriasis and Psoriatic arthritis.

Uveitis, in particular, can be a key symptom that leads to the diagnosis of SpA. Both male and female SpA patients are more likely to experience uveitis if they have radiographic damage and have had the disease for a long time. Patients with uveitis should be referred to a rheumatologist for a comprehensive SpA assessment.

Source: https://www.ajo.com/article/S0002-9394(21)00150-1/fulltext?rss=yes
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