Vancomycin levels are frequently subtherapeutic in criticall
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Appropriate utilization of vancomycin is important to attain therapeutic targets while avoiding clinical failure and the development of antimicrobial resistance. Our aim was to observe the use of vancomycin in an intensive care population, with the main focus on achievement of therapeutic serum concentrations (15–20 mg/l) and to evaluate how this was influenced by dose regimens, use of guidelines and therapeutic drug monitoring........

http://onlinelibrary.wiley.com/doi/10.1111/aas.12897/abstract
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