Ventriculomegaly detected on 20-week anatomic fetal US
The present case has been published in the journal Neurology. A 23-year-old G1P0 woman was referred for fetal MRI after her 20-week anatomic fetal ultrasound demonstrated cerebral ventriculomegaly.

Her pregnancy to date had been uncomplicated without notable fevers, illnesses, or need for medications aside from prenatal vitamins. The fetal MRI obtained at 24 weeks gestation demonstrated a phenotypically male fetus with severely dilated lateral ventricles measuring up to 30 mm with marked thinning of the cortical mantle, aqueductal stenosis, diencephalic fusion, and brainstem dysplasia.

At 33 weeks and 4 days gestation, the mother delivered via cesarean section following premature rupture of membranes. Initial APGARs of the neonate were 8 and 9 at 1 and 5 minutes, respectively. Examination was notable for significant macrocephaly with fronto-orbital circumference 41.5 cm (>99 percentile), distended scalp veins, nondysmorphic facies, and fisted thumbs with an otherwise normal general examination.

His neurologic examination was unremarkable other than significant head lag attributed to his excessively discordant head size. His tone was otherwise within normal limits for a 33-week premature neonate. A postnatal head ultrasound showed severe bilateral lateral ventriculomegaly measuring up to 86 mm in maximum craniocaudal dimension and a nondilated fourth ventricle

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