Virus has mutated into 10 types, one now dominant across reg
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The novel coronavirus has mutated into 10 different types and one of them — A2a — has nearly replaced all the others to become dominant across geographical regions, says a global study by National Institute of Biomedical Genomics.

• Coronavirus can be classified into many types --- O, A2, A2a, A3, B, B1, and so on.
• Currently, there are 11 types, including type O (ancestral type that originated in Wuhan)
• Of them, A2a mutated coronavirus started overtaking other types across the world by March-end.
• A2a, highly efficient in entering human lung cells in larger numbers.
• This mutation altered a component of the spike protein on surface of virus, allowing it to bind more easily with the surface protein of the lung cell
• RNA sequences of 3,600 coronaviruses collected from 55 countries were used in study
• 35 RNA sequences checked from Indian patients and of which 47.5% accounted for A2a
• The study provides specific target to vaccine manufacturers

The study, by Nidhan Biswas and Partha Majumder from the National Institute of Biomedical Genomics in Kalyani, West Bengal, will soon be published in the Indian Journal of Medical Research, a peer-reviewed medical journal published by the Indian Council for Medical Research (ICMR).

Source: https://health.economictimes.indiatimes.com/news/industry/virus-has-mutated-into-10-types-one-now-dominant-across-regions-study/75418508
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Dr. N●●●●a G●●●a
Dr. N●●●●a G●●●a Obstetrics and Gynaecology
Whats the duration of illness ,falality and virulence besides the spread.
Apr 29, 2020Like1
Dr. D●●●●i S●●h
Dr. D●●●●i S●●h General Medicine
The median time from onset to clinical recovery for mild cases is approximately 2 weeks and is 3-6 weeks for patients with severe or critical disease. The COVID-19 virus is much more virulent than either the SARs or MERs virus and its ability to cause serious disease inversely corresponds to the person’s ability to produce T-cells which declines linearly with age. The ACE2 receptor binding site do not vary among different ethnic groups but do in expression levels. This variance in expression level may explain for different infectivity rates among men and women and predict and explain different susceptibilities to infection by different ethnic groups. Furthermore, by understanding the underlying pathophysiology one can explain and provide guidance to the clinical effectiveness of any treatment. For more information refer : https://www.ncbi.nlm.nih.gov/books/NBK554776/ ... Read more
May 1, 2020Like4
H●●●a K●●n
H●●●a K●●n General Medicine
Virus has mutated into 6 clusters only
Jul 22, 2020Like