Visceral Adiposity, Bone Density Show Significant Linkage
This study aimed to explore the relationship between obesity status and bone density mineral (BMD) from a novel perspective of visceral adiposity. It included 9,016 participants from the National Health and Nutrition Examination Survey (NHANES) 2007-2010. The visceral adiposity index (VAI) was calculated by anthropometry parameters (body mass index and waist circumference) and functional parameters (triglycerides and high-density lipoprotein cholesterol). After adjusting for multiple covariates, there was a significant positive correlation between VAI and lumbar spine, total femur, and femoral neck BMD. After converting VAI to a categorical variable (quartiles), participants in the highest VAI quartile had a 0.049g/cm2 higher BMD than those in the lowest VAI quartile. In subgroup analyses stratified by age, the relationship between VAI and lumbar BMD was an inverted U-shaped curve in the age less than 18 groups, with a point of inflection at 4.86.

VAI was significantly positively correlated with lumbar BMD, demonstrating the complex relationship between visceral fat and bone metabolism. In addition, VAI may be used as a useful predictor of osteoporosis and provide new ideas for the evaluation and screening of osteoporosis.