Vitamin D levels and gestational diabetes mellitus
Now open: Certificate Course in Management of Covid-19 by Govt. Of Gujarat and PlexusMDKnow more...Now open: Certificate Course in Management of Covid-19 by Govt. Of Gujarat and PlexusMDKnow more...
Hypovitaminosis D has been associated with adverse pregnancy outcomes like infertility, gestational diabetes mellitus (GDM), preeclampsia, increased rate of cesarean section, bacterial vaginosis, neonatal hypocalcemia, fetal growth restriction (FGR), neonatal seizures. A recent study suggests that Vitamin D supplements during the 2nd trimester of pregnancy reduce the risk of developing GDM.

A randomized, double-blinded, interventional study was conducted on 178 pregnant women of gestational age 13-24 weeks, who were diagnosed to have vitamin D deficiency and at least one risk factor for the development of gestational diabetes mellitus (GDM). 86 women of the interventional group were given oral cholecalciferol sachet 60,000 IU per week till 26th week.

Oral glucose tolerance test carried out between 26-28th weeks revealed that 13.95% in the interventional group developed GDM while 86.05% did not. While 32.61% in the control group developed GDM while 67.39% did not. The difference observed in the development of GDM after supplementation with vitamin D was statistically significant.

In particular, vitamin D supplementation for high-risk pregnant women in the second trimester helps in the prevention of GDM.

Source: https://iog.org.in/index.php/iog/article/view/610/766
Like
Comment
Share
Dr. J●i B●●●●i
Dr. J●i B●●●●i Obstetrics and Gynaecology
👌
Mar 25, 2021Like