Weight Loss Can Prevent Or Even Reverse Diabetes: ESC Study
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Losing weight could prevent or even reverse diabetes, according to late breaking research presented today at ESC Congress 2020.

The study included 445,765 participants of the UK Biobank. The average age was 57.2 years and 54% were women. Inherited risk of diabetes was assessed using 6.9 million genes. Height and weight were measured at enrolment to calculate BMI in kg/m2. Participants were divided into five groups according to genetic risk of diabetes. They were also divided into five groups according to BMI.

Participants were followed-up until an average age of 65.2 years. During that period, 31,298 developed type 2 diabetes.

Those in the highest BMI group (average 34.5 kg/m2) had an 11-fold increased risk of diabetes compared to participants in the lowest BMI group (average 21.7 kg/m2). The highest BMI group had a greater likelihood of developing diabetes than all other BMI groups, regardless of genetic risk.

"The findings indicate that BMI is a much more powerful risk factor for diabetes than genetic predisposition," said researchers.

The investigators then used statistical methods to estimate whether the likelihood of diabetes in people with a high BMI would be even greater if they were overweight for a long period of time. They found that the duration of elevated BMI did not have an impact on the risk of diabetes.

This suggests that when people cross a certain BMI threshold, their chances of diabetes go up and stay at that same high-risk level regardless of how long they are overweight.

"It may also be possible to reverse diabetes by losing weight in the early stages before permanent damage occurs," said researchers.

Source: https://www.escardio.org/The-ESC/Press-Office/Press-releases/Body-mass-index-is-a-more-powerful-risk-factor-for-diabetes-than-genetics
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Dr. R●●●●●●●●●n C●●●●●●t Internal Medicine
DIRECT TRIAL also has shown similar results.
Aug 31, 2020Like