Wells syndrome with marked swelling in the hands: Case repor
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Wells syndrome is a relapsing eosinophilic dermatitis with variable clinical appearance. Due to symptoms of erythema and swelling of the limbs, it is often misdiagnosed as cellulitis or contact dermatitis. However, cases of Wells syndrome with extending swelling from the arms to hands are rare.

A 61-year-old woman with hemorrhoids and arterial hypertension presented with painful swelling, erythema, purple spots, and blisters on both hands, from fingers to wrists. Hemorrhagic plaques were observed in the palms. She had difficulty in bending her fingers and had finger sclerotic edema, which exhibited sausage-like swelling. In addition, her trunk and extremities were erythematous with itching. The initial clinical diagnosis made by a local hospital had been contact dermatitis, and she was treated with oral prednisolone (10 mg/day), which improved her symptoms. A biopsy specimen taken from the right thumb.

The patient was diagnosed with Wells syndrome and was successfully treated with betamethasone butyrate propionate ointment and olopatadine hydrochloride tablets.

Source: https://www.idoj.in/article.asp?issn=2229-5178;year=2020;volume=11;issue=6;spage=979;epage=982;aulast=Watanabe
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