When It Comes to Hypothermia Post–Cardiovascular Surgery, Go
When it comes to mitigating against postoperative cognitive decline and preserving functional brain connectivity after circulatory arrest for aortic arch surgery, deep hypothermia is superior to high-moderate hypothermia, a pilot study has concluded. A larger prospective trial is underway to confirm these results.
“Deep hypothermia—which constitutes cooling the body to a temperature of less than or equal to 20° C—has ushered in the modern era of safe and effective aortic arch surgery,” said Rebecca Y. Klinger, MD, assistant professor of anesthesiology at Duke University Medical Center, in Durham, N.C. “This process allows for safe circulatory arrest, because a progressive reduction in brain temperature leads to a reduction in the cerebral metabolic rate of oxygen.”...