Woman with Pregnancy and Lactation-Associated Osteoporosis (
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The patient is a 24-year-old woman complaining of severe back pain. The patient was under medical treatment, but the nonsteroidal anti-inflammatory drugs (NSAIDs) along with physiotherapy had nothing to alleviate the pain. In the thoracolumbar radiographs, a loss of vertebral height in the T11-L5 was detected.

In the same area, multiple compression fractures were illustrated through (MRI) (Figure 1). The dual-energy X-ray absorptiometry (Hologic Discovery system) was applied to quantify the bone mineral density (BMD) at the vertebral spine and the hip. The BMD confirmed the osteoporosis. In addition, the patient was suffering from abdominal pain and anemia. Gastrointestinal examinations and related tests were normal as reported by the gastroenterologist. Only anemia due to iron deficiency was reported by an oncologist for further blood tests. Other examinations were healthy.

The patient was advised to discontinue lactation as soon as PLO was established. Immediately, author prescribed calcium 500 mg per day, vitamin D3 50000 every 2 weeks, and teriparatide 20 g/d. An improvement in the patient’s pain and movement was seen three weeks after the therapy. As far as the spinal and hip BMD is concerned, the control BMD was shown to be increased 18 months after the treatment.

Source:https://www.hindawi.com/journals/criog/2020/8836583/
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