Xanthogranulomatous oophoritis mimicking an ovarian neoplasm
Xanthogranulomatous inflammation of female genital tract is uncommon and is usually seen in endometrium. Only a few cases involving the ovary have been reported. Its clinical manifestations, imaging modalities, and gross features can mimic ovarian malignancy. Thus, a preoperative diagnosis of this entity is important to avoid radical surgical treatment.

Published in the Journal of Mid Life Health, the authors report a case of xanthogranulomatous oophoritis in a 24 years female, which was clinically and radiologically misdiagnosed as ovarian neoplasm. The approach to such a case and the differential diagnosis has also been discussed.

A 24-year-old P3L3A3 female presented with the chief complaints of pain abdomen on and off, and heavy irregular cycles for 6 months. On per vaginal examination, a firm left adnexal mass could be palpated. Her blood investigations revealed microcytic hypochromic anemia, slight raise in total leukocyte count (12,000/L), raised erythrocyte sedimentation rate (ESR) (45 mm at 1st h), and slightly raised lactate dehydrogenase (490 IU/L).

Contrast-enhanced computed tomography abdomen was performed, which showed a left adnexal mass, measuring 8.5 cm × 6.8 cm × 6.3 cm, causing displacement of surrounding bowel loops and lateral displacement of uterus. The mass was multiloculated, cystic with enhancing irregular walls and multiple septations. The possibility of a benign neoplasm (cystadenoma) was suggested.

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