Acquired cutis laxa presenting as pedunculated eyelid plaque
The present case has been reported in the journal Ophthalmology.

A 72-year-old woman without known familial skin disease presented with a 10-year history of slowly progressive pedunculated upper eyelid and glabellar plaques (Fig A). Excisional biopsy with Verhoeff-van Gieson staining demonstrated extensive dermal fibrosis with only rare residual elastic fibers (Fig B).

The characteristic features on pathology, late onset of findings, and lack of intraocular or systemic manifestations in our patient were consistent with a diagnosis of acquired cutis laxa. Cutis laxa is a rare inherited or acquired connective tissue disorder. Multiple systemic conditions, inflammatory dermatoses, and medications have been associated with acquired cutis laxa, though its definitive etiology remains unclear.

Acquired cutis laxa has rarely been reported to involve the eyelids. Excision is helpful but repeated procedures are often necessary due to recurrence.

Read more here: