Anesthesia’s Cognitive Effects In Young Children Vary by Age
An association between multiple exposures to general anesthesia in the first two years of life and increased risk for neurocognitive impairment was not found in two large Canadian studies. Exposures from 2 to 4 years of age, however, were another matter.

“It remains uncertain whether the anesthetic neurotoxicity that’s been clearly demonstrated in animal studies is of concern to our pediatric patients,” said M. Ruth Graham, MD, associate professor of anesthesia at the University of Manitoba, in Winnipeg. “And while two of the ongoing prospective studies have been reassuring in this regard, both are limited by the fact that they examined a single anesthetic exposure of fairly short duration.”.....