Even Mild Obesity Raises Severe COVID-19 Risks: An Italian S
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People with a body mass index of 30 kg/m square or above are at significantly increased risk for severe COVID-19, while a BMI of 35 and higher dramatically increases the risk for death, new research suggests. The data, from nearly 500 patients hospitalized with COVID-19 were published in the European Journal of Endocrinology.

The data support the recent change by the CDC to lower the cutoff for categorizing a person at increased risk from COVID-19 from a BMI of 40 down to 30.

The study included 482 adults admitted with confirmed COVID-19 to a single Italian hospital. Of those, 41.9% had a BMI of less than 25 (normal weight), 36.5% had a BMI of 25-29.9 (overweight), and 21.6% had BMI of at least 30 (obese). Of the obese group, 20 (4.1%) had BMIs of at least 35, while 18 patients (3.7%) had BMIs of less than 20 (underweight).

Among those with obesity, 51.9% experienced respiratory failure, 36.4% were admitted to the ICU, 25% required mechanical ventilation, and 29.8% died within 30 days of symptom onset.

Patients with BMIs of at least 30 had significantly increased risks for respiratory failure, ICU admission, and death, compared with those with lower BMIs. Within the group classified as obese, the risks of respiratory failure and ICU admission were higher, with BMIs of 30-34.9 and for BMIs of at least 35. The risk of death was significantly higher among patients with a BMI of at least 35.

Every 1-unit increase in BMI was significantly associated with all outcomes, but there was no significant difference in any outcome between the 25-29.9 BMI category and normal weight. In all models, the BMI cutoff for increased risk was 30.

Source: https://eje.bioscientifica.com/view/journals/eje/aop/eje-20-0541/eje-20-0541.xml
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