Functional outcomes and Quality of Life after Redo Anastomos
Redo anastomosis can be considered in selected patients with persistent leakage, stenosis, or local recurrence.

The aim of this study was to compare functional outcomes and the quality of life between redo anastomosis and primary successful anastomosis following total mesorectal excision for rectal cancer.

Patients undergoing redo anastomosis were compared with patients with a primary successful anastomosis after total mesorectal excision for rectal cancer. In total, 170 patients were included; 52 underwent redo anastomosis and 118 were controls.

- Major low anterior resection syndrome occurred in 73% after redo anastomosis compared with 68% following primary successful anastomosis.

- The redo group had worse EORTC QLQ-CR29 mean scores for fecal incontinence and flatulence.

- There were no differences in urinary or sexual dysfunction, either in men or in women.

- Significantly worse scores in the redo group were found for global health, role and social function, body image, and anxiety.

In particular, redo anastomosis is associated with significantly worse quality of life compared with primary successful anastomosis. However, major low anterior resection syndrome was comparable between groups and should not be a reason to preclude restoration of bowel continuity in highly motivated patients.

Diseases of the Colon & Rectum