Giant leiomyosarcoma of the inferior vena cava necessitating
Leiomyosarcoma of the inferior vena cava (IVC) is a rare malignant tumor of smooth muscle origin. It commonly presents with non-specific symptoms including abdominal pain, distention, and lower extremity edema. Surgical resection with macroscopically clear margins is the only potentially curative treatment for the disease.

Here doctors present the case of a previously healthy 38-year-old woman with a subacute one-month increase of a four-year slowly progressive right-sided abdominal pain and back pain.

Imaging revealed a 14.5x12x15cm mass in the right hepatic lobe causing mass effect on adjacent abdominal and retroperitoneal organs and involving the retrohepatic IVC.

En-bloc resection of the right hemi-liver, most of segment four, the caudate lobe, and approximately a 10 cm section of the retrohepatic IVC, along with IVC reconstruction, was performed. Histologic examination revealed the diagnosis of a high-grade leiomyosarcoma.

In conclusion, the current treatment for IVC leiomyosarcoma is surgical resection seeking macroscopically clear margins, with or without IVC reconstruction.

Journal of Surgical Case Reports