Importance of Early Joint Replacement in Juvenile Idiopathic
A Study was conducted to describe early prosthesis implantations in a cohort of patients with juvenile idiopathic arthritis (JIA) followed in a tertiary referral hospital and to analyze possible factors influencing implant survival.

This was a retrospective cohort study. Charts of all patients with JIA who underwent total joint replacement were analyzed.

--85 patients met the inclusion criteria for this study, with a median follow-up period of 17.2 years. The median age at first prosthesis was 22.7 years. The total number of replaced joints was 198 over a period of 27 years.

--The hip was the most frequently replaced joint, accounting for almost two-thirds of the total number of implants; the other one-third refers mostly to knee implants.

--Polyarticular JIA and systemic JIA were the most represented JIA categories in the study cohort. A significant upward trend of the age at arthroplasty and of disease duration before arthroplasty over decades was found.

--The rates of implant survival at 5, 10, and 15 years were comparable (from 84% to 89%); 50% of implants lasted more than 20 years.

Over time, there was a progressive and substantial rising trend in both age at arthroplasty and disease duration prior to the first arthroplasty. The JIA category, year of implant, and presence of comorbidities all had a substantial impact on implant survival.