Insulin Delivery By Pen Linked To Better Control Of Blood Su
As compared to a syringe, delivery of insulin by pen shows more reduction in HbA1c in diabetic patients at 24 weeks of follow-up, suggests a study. Comparing the use of pens with syringes to apply insulin among elderly patients with type 2 DM, the researchers found no difference regarding the frequency of hypoglycemia, the need for higher doses of insulin or other medications.

This insulin can be delivered via pens and syringes. However, the use of pens application seems to be more feasible; but its influence on controlling blood sugar levels in elderly people has not been clearly defined yet. A study was conducted by a group of researchers from Brazil to investigate the influence of delivery of insulin through pen on blood sugar levels.

The researchers conducted a clinical trial for comparing pens and syringes for insulin application among patients with type 2 diabetes mellitus over 60 years old and glycated hemoglobin greater than 8.5% at baseline. They selected a total of 121 patients with a mean age of 65.75 years. Out of which 61 were randomized for pen group (PG) and 60 patients for the syringe group (SG). Their follow-up was at 24 weeks, with monthly medical visits to adjust the treatment. All patients received either received just insulin NPH and, if required, insulin Regular.

They evaluated the glycemic control, treatment adherence, hypoglycemia occurrence, need for adjustment in treatment, and impact on quality of life.

The results of the study are as follows:

· At baseline, mean HbA1c was 10.34±1.66% in the pen group and 9.90±1.25% in the syringe group.
· Mean HbA1c was 8.39±1.28% in the pen group and 8.85±1.74% in the syringe group at 24 weeks.
· However, there was a more reduction in pen group during follow-up.
· While they found no difference in treatment adherence rates, hypoglycemia, greater need for insulin doses or oral medication, and progression to basal-bolus insulin scheme.
· They also found no difference in the impact of the disease on the quality of life between groups.

The researchers concluded that though they did not find any difference in the impact on quality of life, frequency of hypoglycemia, or adherence, the pen the group showed a reduction in HbA1c higher in 24 weeks of follow-up.

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