Irish scientists discover why some cancer patients don’t res
GROUND-BREAKING cancer research in Ireland has pinpointed the reason why some patients are resistant to treatment for oesophageal cancer.

Oesophageal adenocarcinoma is a cancer of the food-pipe.It has seen an increase of 600 per cent over the past three decades worldwide and rates are projected to continue increasing over the next 20 years.

For the first time, a team of cancer researchers at Trinity College Dublin have discovered the molecule absent from the cancer stem cell, miR-17, that proves resistant to the radiotherapy treatment used to treat the cancer.The team was led by Dr Stephen Maher, Ussher Assistant Professor in Translational Oncology.

He said: “This work is extremely important in understanding why tumours are inherently resistant to radiotherapy and how they can acquire resistance.

“Our findings strongly suggest that it is the cancer stem cell population that we need to destroy if treatment is going to be effective in our oesophageal cancer patients.”