Maternal and perinatal outcome in pregnancy complicated by o
Intrahepatic cholestasis of pregnancy (IHCP) is the most common pregnancy-related liver disorder. It typically presents with troublesome itching and can lead to complications for both mother and fetus.

It was a prospective epidemiological study during a period of one year over 120 pregnant ladies suffering from pruritus and detected as having Obstetric Cholestasis. They were followed up and maternal as well as perinatal outcomes recorded.

- The incidence of Obstetric Cholestasis in the hospital was 9.3%. The majority of cases were delivered at term.

- 41.6% of patients were delivered vaginally, 43.3% had an emergency cesarean section, and 2.5% of patients had instrumental delivery.

- Maternal morbidities are due to sleep disturbance, coagulation abnormality, increase the chance of operative delivery, and postpartum hemorrhage.

- Neonatal complications include meconium aspiration, NICU admission, prematurity, and perinatal mortality.

Conclusively, cholestasis of pregnancy causes maternal pruritus with impaired liver function tests. Maternal morbidity is increased in terms of increased cesarean section rates and discomfort due to pruritus. Timely intervention at 37-38 weeks will reduce the adverse perinatal outcome.

International Journal of Reproduction, Contraception, Obstetrics & Gynecology
Source: https://dx.doi.org/10.18203/2320-1770.ijrcog20212676
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