New-onset Atrial Fibrillation after Cardiac Surgery is a Sig
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This study sought to determine the incidence and significance of new-onset atrial fibrillation as a risk factor for long-term stroke and mortality after cardiac surgery. A prospective cohort study in 2 large tertiary public hospitals was carried out.

The study comprised 3008 patients who underwent coronary artery bypass grafting and/or valve surgery from 2008 to 2012.

New-onset atrial fibrillation was analysed as a risk factor for postoperative stroke using a multivariable logistic regression model following adjustment for potential confounders. A Cox regression model with time-dependent variables was used to analyse relationships between new-onset atrial fibrillation and postoperative survival.

New-onset atrial fibrillation was detected in 573 (19.0%) patients. Stroke occurred in 234 (7.8%) patients over the mean postoperative follow-up period of 6 ± 2 years. The incidence of postoperative stroke in patients with new-onset atrial fibrillation (9.9%) and patients with both preoperative and postoperative atrial fibrillation (13.8%) was higher than patients with no atrial fibrillation (6.8%).

New-onset atrial fibrillation was identified as an independent risk factor for postoperative stroke. 518 (17.2%) mortalities occurred within the mean postoperative follow-up period of 8 ± 2 years. New-onset atrial fibrillation was associated with shorter survival compared to patients with no atrial fibrillation.

Conclusively, new-onset atrial fibrillation is a significant risk factor for long-term stroke and mortality after cardiac surgery. Close monitoring and treatment of this condition may be necessary to reduce the risk of postoperative stroke and mortality.