Penile gangrene in chronic renal failure and DM: a rare case
Penile gangrene is a disease difficult to be treated. Its genesis might be infectious, traumatic or vascular. Usually, diabetes mellitus causes vascular changes with subsequent vascular atherosclerosis and chronic renal failure.

The calcium-phosphate metabolism is disrupted by small cell vessel calcification in 1–4% of cases. The present case has been reported in the journal Urology Case Reports.

The authors report here a case of penile gangrene due to penile calciphylaxis in a patient with diabetes mellitus and chronic renal failure. Initially the patient demonstrated dry gangrene of the glans penis, which turned to wet after partial amputation. The main cause of the gangrene was considered to be circulatory insufficiency induced by severe arteriosclerosis.

Major takeaway:-
- Despite high mortality rate associated with ischaemic penile gangrene aggressive management is recommended for those who are not terminal.

- Parathyroidectomy, low molecular heparin and hyperbaric oxygen therapy are applied for the treatment of calciphylaxis and the hyperphosphatemia and hypocalcaemia correction.

- The surgical management of ischemic penile gangrene is necrectomy and later plastic reconstruction of the affected area.

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