Primary signet ring cell carcinoma of the cervix: a rare dia
Most cervical adenocarcinomas are of the endocervical type, and the other subtypes are less common. Primary cervical signet ring cell carcinoma (PCSRCC) is extremely rare, and it is mostly a metastasis of cancers originating in other organs such as the stomach, breast, colon/rectum, or ovaries. The present case has been published in the Taiwanese Journal of Obstetrics and Gynecology.

The 48-year-old woman visited the gynecological department because of postmenopausal bleeding. A cervical mass was discovered through pelvic examination, and the biopsy results indicated a poorly differentiated adenocarcinoma with a signet ring cell pattern.

Colonoscopy revealed external compression of the rectum without intraluminal mucosal lesions. Abdominal computed tomography revealed a suspicious malignant lesion at the cervicorectal junction and multiple metastases.

Debulking surgery was performed and the final pathology report documented a FIGO stage IVb PCSRCC involving multiple sites.

Key takeaway:-
- Complete tumor survey and staging are critical to differentiate primary from metastatic signet cell carcinoma of the cervix.

- Thus, diagnosis must sometimes be made by exclusion.

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