Rapidly progressing glomerulonephritis in pregnancy with suc
Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a systemic autoimmune disease of unknown aetiology that involves small to medium-sized blood vessels. It causes small vessel vasculitis and inflammatory damage to kidneys, lungs and upper airways. These lead to acute renal failure, pulmonary haemorrhage and musculoskeletal damage.

The clinical manifestations are oliguria, hematuria, high blood pressure, anaemia, oedema and joint aches. AAV is commonly diagnosed between the fifth and seventh decade of life. The disease is not frequently reported in 4 women of early reproductive age.

Pregnancy in patients with an-neutrophil cytoplasm antibody–associated vasculitis is associated with a high risk of foetal and maternal complications. The present case is a rare one of a patient having RPGN (Rapidly progressing glomerulonephritis) in the pregnancy that continued till 32 weeks and had a successful foetal outcome.

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