Root Canal Bacteria Can Worsen Other Diseases: Because a root canal tooth is technically infected, it can contribute to certain health problems which include heart disease, according to Kulacz. He says that heart diseases are generally caused by damage to the inside lining of the blood vessel and migration and macrophages and cholesterol inside that artery. The inflammation in the artery causes plaque to rupture into the space of the blood vessel. This causes a blood clot and a heart attack. This same bacteria that is found in root canal teeth and gum disease are also found in the plaques of coronary arteries in the blood clots, says Kulacz. The plaque travels from the mouth to other sites of the body.