Study finds, Adolescent eating disorder with catheter-relate
Treatment of adolescent eating disorder requires early improvement of nutritional status. Central venous hyperalimentation is used but catheter-related bloodstream infection (CRBSI) is a complication.

The subjects were 51 patients who received nutritional therapy with the use of a peripherally inserted central catheter (PICC). The courses of weight and white blood cell (WBC) count were examined retrospectively during nutritional therapy. Onset factors for CRBSI were determined and a case series of CRBSI caused by Candida parapsilosis was presented.

Results:
--The day of minimum weight occurred on or before day 7 in 37 of the 51 patients, and this day was preceded by the day with the lowest WBC at a significant rate.

--The minimum weight day was significantly delayed in CRSBI cases compared with non-CRBSI cases.

--In the case series of CRBSI caused by C. parapsilosis, the median WBC count before CRBSI decreased to 2,570/microL at a median of day 36.

--Catheter-related bloodstream infection developed at a median of day (26–133) 38.

--The PICC was immediately removed and an antifungal drug was started, leading to cure with no after effects in all subjects.

Finally, excessive resistance to weight gain became a risk factor for developing catheter-related bloodstream infection in patients with an eating disorder who were treated with nutritional therapy using a peripherally inserted central catheter. Also with increased appetite and weight gain, white blood cell counts rebound, suggesting that there is a chance of developing CRBSI.

Source: https://onlinelibrary.wiley.com/doi/10.1111/ped.14511?af=R
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May 5, 2021Like