Study finds, Long term outcomes in fellow eyes comparing DSA
A Study was conducted to compare the long term results of Descemet's stripping automated endothelial keratoplasty (DSAEK) and Descemet's membrane endothelial keratoplasty (DMEK) in fellow eyes for treatment of Fuchs endothelial corneal dystrophy (FED).

Two-centered, retrospective case series of 64 patients (128 eyes) with DSAEK followed by DMEK were included. The main outcomes measured were BSCVA and duration of time to achieve BSCVA as well as eye preference.

--Preoperative median logarithm of the minimum angle of resolution (logMAR) BSCVA was similar in eyes receiving DMEK 0.36±0.26 and DSAEK 0.42±0.34.

--Average follow up time needed for the DMEK eyes to achieve BSCVA was faster than that of DSAEK (277 days versus 490 days).

--With long term follow-up BSCVA of the DMEK eyes did not show a statistically significant difference.

--22 of the 64 preferred the DMEK eye, 17 patients preferred the DSAEK eye while 25 patients did not have a preference.

--In the DMEK group the average spherical equivalent was -0.08 compared to DSAEK group at 0.06.

Finally, DMEK and DSAEK exhibited equivalent BSCVA levels and patient satisfaction with long-term follow-up. The DMEK eyes reached their BSCVA early, but over a longer time frame the DSAEK eyes improved. In the DMEK group, a greater number of patients had 20/25 and 20/20 visions but statistically the difference was not significant.